Replication Termination Factor 2 (RTF2) (AA 4-306) Antikörper (Fluoro594)

Produktnummer ABIN8031601

Der Fluoro594-konjugierte Kaninchen Polyklonal anti-Replication Termination Factor 2 Antikörper (ABIN8031601) detektiert spezifisch Replication Termination Factor 2 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Replication Termination Factor 2 (RTF2) (AA 4-306) Antikörper (Fluoro594) (ABIN8031601)

Target: Replication Termination Factor 2 (RTF2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails

Bindungsspezifität: AA 4-306

Verwendungszweck: Anti-RTF2 Antibody Fluoro594 Conjugated

Homologie: Human RTF2 shares 87.8%,88.1% amino acid (aa) sequence identity with mouse,rat RTF2,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RTF2 recombinant protein (Position: D4-F306). Human RTF2 shares 87.8% and 88.1% amino acid (aa) sequence identity with mouse and rat RTF2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Antigendetails

Target: Replication Termination Factor 2 (RTF2)

Andere Bezeichnung: RTF2

Hintergrund:

Background: Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. Replication Termination Factor 2, often abbreviated as RTF2, is a protein involved in the regulation and termination of DNA replication processes in eukaryotic cells. It plays a crucial role in ensuring the accurate completion of DNA synthesis during cell division by coordinating the termination of replication forks at specific sites along the DNA strands. RTF2 functions by interacting with other proteins and DNA sequences to facilitate the orderly disassembly of the replication machinery and the prevention of unnecessary re-replication of genomic regions. Its activity is tightly regulated to maintain genomic stability and fidelity, making it a key player in cell cycle control mechanisms. Studies on RTF2 have provided insights into the molecular mechanisms governing DNA replication termination and its implications for cellular function and genome maintenance.

Gene Full Name: replication termination factor 2

Gen-ID: 51507

UniProt: Q9BY42