RGS18 Antikörper (AA 1-230) (Fluoro550)

Produktnummer ABIN8031214

Der Fluoro550-konjugierte Kaninchen Polyklonal anti-RGS18 Antikörper (ABIN8031214) detektiert spezifisch RGS18 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RGS18 Antikörper (AA 1-230) (Fluoro550) (ABIN8031214)

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS18 Antikörper ist konjugiert mit Fluoro550

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RGS18 Antikörper (Fluoro550)

Bindungsspezifität: AA 1-230

Verwendungszweck: Anti-RGS18 Antibody Fluoro550 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RGS18 recombinant protein (Position: M1-D230).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RGS18

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Andere Bezeichnung: RGS18

Hintergrund:

Background: Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gene Full Name: regulator of G protein signaling 18

Gen-ID: 64407

UniProt: Q9NS28

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling