RASD1 Antikörper (AA 1-281) (Cy3)

Produktnummer ABIN8030805

Der Kaninchen Polyklonal anti-RASD1 Antikörper wird verwendet zum Nachweis von RASD1 in Proben von Maus, Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für RASD1 Antikörper (AA 1-281) (Cy3) (ABIN8030805)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RASD1 Antikörper (Cy3)

Bindungsspezifität: AA 1-281

Verwendungszweck: Anti-Dexras1/RASD1 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Dexras1/RASD1 recombinant protein (Position: M1-S281).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Andere Bezeichnung: RASD1

Hintergrund:

Background: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: ras related dexamethasone induced 1

Gen-ID: 51655

UniProt: Q9Y272