RAD51AP1 Antikörper (AA 1-303) (HRP)

Produktnummer ABIN8030123

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAD51AP1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RAD51AP1 Antikörper (AA 1-303) (HRP) (ABIN8030123)

Target: RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51AP1 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RAD51AP1 Antikörper (HRP)

Bindungsspezifität: AA 1-303

Verwendungszweck: Anti-RAD51AP1 Antibody HRP Conjugated

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RAD51AP1 recombinant protein (Position: M1-K303).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAD51AP1

Target: RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))

Andere Bezeichnung: RAD51AP1

Hintergrund:

Background: The RAD51AP1 gene encodes a protein known as RAD51-associated protein 1, which plays a crucial role in homologous recombination, a DNA repair pathway essential for maintaining genomic integrity. RAD51AP1 interacts with RAD51, a key protein involved in homologous recombination, and promotes the assembly of RAD51 nucleoprotein filaments on single-stranded DNA, facilitating the search for homologous sequences and strand exchange. This process is vital for repairing DNA double-strand breaks and stalled replication forks, as well as for meiotic recombination and telomere maintenance. Dysregulation of RAD51AP1 expression or function has been implicated in cancer development and progression, as defects in homologous recombination can lead to genomic instability and oncogenesis. Understanding the molecular mechanisms underlying RAD51AP1-mediated homologous recombination is crucial for deciphering its role in DNA repair and genome maintenance, as well as for developing targeted therapies for cancer and other diseases associated with DNA damage.

Gene Full Name: RAD51 associated protein 1

Gen-ID: 10635

UniProt: Q96B01