RAB7A Antikörper (AA 21-177) (Fluoro550)
Kurzübersicht für RAB7A Antikörper (AA 21-177) (Fluoro550) (ABIN8029966)
Target
Alle RAB7A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-177
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Verwendungszweck
- Anti-RAB7/RAB7A Antibody Fluoro550 Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human RAB7/RAB7A recombinant protein (Position: K21-E177).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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Andere Bezeichnung
- RAB7A
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Hintergrund
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Background: Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end ed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
Gene Full Name: RAB7A, member RAS oncogene family
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Gen-ID
- 7879
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UniProt
- P51149
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Pathways
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom
Target
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