RAB36 Antikörper (AA 56-323) (Fluoro488)

Produktnummer ABIN8029833

Der Kaninchen Polyklonal anti-RAB36 Antikörper wird verwendet zum Nachweis von RAB36 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für RAB36 Antikörper (AA 56-323) (Fluoro488) (ABIN8029833)

Target: RAB36 (RAB36, Member RAS Oncogene Family (RAB36))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB36 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-RAB36 Antikörper (Fluoro488)

Bindungsspezifität: AA 56-323

Verwendungszweck: Anti-RAB36 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RAB36 recombinant protein (Position: Q56-E323).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu RAB36

Target: RAB36 (RAB36, Member RAS Oncogene Family (RAB36))

Andere Bezeichnung: RAB36

Hintergrund:

Background: Ras-related protein Rab-36 is a protein that in humans is encoded by the RAB36 gene. The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 36 is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it is believed to participate in protein transport. The gene encoding Rab 36 localizes to a critical region of chromosome 22 that is often deleted or involved in translocations in malignant rhabdoid tumors (MRTs). This suggests that Rab 36 may play a role in the development of MRTs.

Gene Full Name: RAB36, member RAS oncogene family

Gen-ID: 9609

UniProt: O95755