PHTF1 Antikörper (AA 188-430) (Cy3)

Produktnummer ABIN8029123

Der Cy3-konjugierte Kaninchen Polyklonal anti-PHTF1 Antikörper (ABIN8029123) detektiert spezifisch PHTF1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PHTF1 Antikörper (AA 188-430) (Cy3) (ABIN8029123)

Target: PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHTF1 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PHTF1 Antikörper (Cy3)

Bindungsspezifität: AA 188-430

Verwendungszweck: Anti-PHTF1 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PHTF1 recombinant protein (Position: I188-Q430).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PHTF1

Target: PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))

Andere Bezeichnung: PHTF1

Hintergrund:

Background: HTF1 (putative homeodomain transcription factor 1), also known as PHTF, is a potential transcription regulator. It is a ubiquitously expressed integral, multipass membrane protein with predominant expression in testis. PHTF1 is associated with the ER (endoplasmic reticulum) and contains one bHLH (basic helix-loop-helix) domain. It is present in the cell during meiosis and spermiogenesis but, by the end of spermiogenesis, is released from the mature cell within the residual bodies. This implies that PHTF1 may play a role in the spermatozoa maturation process. In addition, PHTF1 is believed to interact with FEM1B and may be responsible for recruiting FEM1B to the surface of the ER membrane. This suggests that PHTF1 acts as a sequestering or anchoring protein for FEM1B. Two PHTF1 isoforms exist due to alternate splicing events. Isoform 2 is the shorter form and lacks the amino acid residues 648 to 762.

Gene Full Name: putative homeodomain transcription factor 1

Gen-ID: 10745

UniProt: Q9UMS5