Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) Antikörper (Cy3)

Produktnummer ABIN8028748

Der Cy3-konjugierte Kaninchen Polyklonal anti-Protocadherin gamma Subfamily C, 3 Antikörper (ABIN8028748) detektiert spezifisch Protocadherin gamma Subfamily C, 3 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) Antikörper (Cy3) (ABIN8028748)

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails

Bindungsspezifität: AA 498-804

Verwendungszweck: Anti-PCDHGC3 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHGC3 recombinant protein (Position: E498-E804).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Antigendetails

Target: Protocadherin gamma Subfamily C, 3 (PCDHGC3)

Andere Bezeichnung: PCDHGC3

Hintergrund:

Background: Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily C, 3

Gen-ID: 5098

UniProt: Q9UN70