PCMT1 Antikörper (AA 1-227) (FITC)

Produktnummer ABIN8028576

Der Kaninchen Polyklonal anti-PCMT1 Antikörper wird verwendet zum Nachweis von PCMT1 in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für PCMT1 Antikörper (AA 1-227) (FITC) (ABIN8028576)

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCMT1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PCMT1 Antikörper (FITC)

Bindungsspezifität: AA 1-227

Verwendungszweck: Anti-PCMT1 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PCMT1 shares 96%,95.6% amino acid (aa) sequence identity with mouse,rat PCMT1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PCMT1 recombinant protein (Position: M1-K227). Human PCMT1 shares 96% and 95.6% amino acid (aa) sequence identity with mouse and rat PCMT1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PCMT1

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Andere Bezeichnung: PCMT1

Hintergrund:

Background: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase

Gen-ID: 5110

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization