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PPARA Antikörper (pSer12) (FITC)

Der Kaninchen Polyklonal Anti-PPARA-Antikörper wurde für WB, FACS, IF (p) und IF (cc) validiert. Er ist geeignet, PPARA in Proben von Human, Maus und Ratte zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN753170

Kurzübersicht für PPARA Antikörper (pSer12) (FITC) (ABIN753170)

Target

Alle PPARA Antikörper anzeigen
PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reaktivität

  • 112
  • 92
  • 71
  • 18
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 110
  • 20
Kaninchen

Klonalität

  • 111
  • 19
Polyklonal

Konjugat

  • 71
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PPARA Antikörper ist konjugiert mit FITC

Applikation

  • 114
  • 44
  • 40
  • 38
  • 38
  • 25
  • 20
  • 17
  • 16
  • 15
  • 9
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • Bindungsspezifität

    • 16
    • 15
    • 15
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer12

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Dog,Cow,Pig,Horse,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human PPAR alpha around the phosphorylation site of ser12

    Isotyp

    IgG
  • Applikationshinweise

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Mölzer, Wallner, Kern, Tosevska, Schwarz, Zadnikar, Doberer, Marculescu, Wagner: "Features of an altered AMPK metabolic pathway in Gilbert's Syndrome, and its role in metabolic health." in: Scientific reports, Vol. 6, pp. 30051, (2016) (PubMed).

  • Target

    PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

    Andere Bezeichnung

    PPAR alpha

    Hintergrund

    Synonyms: PPAR, NR1C1, hPPAR, PPARalpha, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA

    Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

    Gen-ID

    5465

    UniProt

    Q07869

    Pathways

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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