PRMT6 Antikörper (AA 45-348) (Fluoro594)

Produktnummer ABIN8027117

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRMT6 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PRMT6 Antikörper (AA 45-348) (Fluoro594) (ABIN8027117)

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT6 Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PRMT6 Antikörper (Fluoro594)

Bindungsspezifität: AA 45-348

Verwendungszweck: Anti-PRMT6 Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PRMT6 recombinant protein (Position: Q45-D348).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PRMT6

Target: PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))

Andere Bezeichnung: PRMT6

Hintergrund:

Background: Protein arginine N-methyltransferase 6 is an enzyme that in humans is encoded by the PRMT6 gene. The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.

Gene Full Name: protein arginine methyltransferase 6

Gen-ID: 55170

UniProt: Q96LA8