PSMA5 Antikörper (AA 1-241) (Fluoro488)

Produktnummer ABIN8026948

Der Fluoro488-konjugierte Kaninchen Polyklonal anti-PSMA5 Antikörper (ABIN8026948) detektiert spezifisch PSMA5 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für PSMA5 Antikörper (AA 1-241) (Fluoro488) (ABIN8026948)

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA5 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PSMA5 Antikörper (Fluoro488)

Bindungsspezifität: AA 1-241

Verwendungszweck: Anti-PSMA5 Antibody Fluoro488 Conjugated

Homologie: Human PSMA5 shares 100%,98.8% amino acid (aa) sequence identity with mouse,rat PSMA5,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PSMA5 recombinant protein (Position: M1-I241). Human PSMA5 shares 100% and 98.8% amino acid (aa) sequence identity with mouse and rat PSMA5, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PSMA5

Target: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Andere Bezeichnung: PSMA5

Hintergrund:

Background: Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.

Gene Full Name: proteasome 20S subunit alpha 5

Gen-ID: 5686

UniProt: P28066

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA