PCCA Antikörper (AA 403-728) (Biotin)
Kurzübersicht für PCCA Antikörper (AA 403-728) (Biotin) (ABIN8026137)
Target
Alle PCCA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 403-728
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Verwendungszweck
- Anti-PCCA Antibody Biotin Conjugated
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Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
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Homologie
- Human PCCA shares 89.6%,89% amino acid (aa) sequence identity with mouse,rat PCCA,respectively.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human PCCA recombinant protein (Position: E403-E728). Human PCCA shares 89.6% and 89% amino acid (aa) sequence identity with mouse and rat PCCA, respectively.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- PCCA (Propionyl CoA Carboxylase, alpha Polypeptide (PCCA))
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Andere Bezeichnung
- PCCA
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Hintergrund
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Background: The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: propionyl-CoA carboxylase subunit alpha
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Gen-ID
- 5095
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UniProt
- P05165
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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