PUF60 Antikörper (AA 48-559) (FITC)

Produktnummer ABIN8023925

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PUF60 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PUF60 Antikörper (AA 48-559) (FITC) (ABIN8023925)

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PUF60 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PUF60 Antikörper (FITC)

Bindungsspezifität: AA 48-559

Verwendungszweck: Anti-PUF60 Antibody FITC Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PUF60 shares 98.8% amino acid (aa) sequence identity with both mouse,rat PUF60.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PUF60 recombinant protein (Position: Q48-A559). Human PUF60 shares 98.8% amino acid (aa) sequence identity with both mouse and rat PUF60.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PUF60

Target: PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))

Andere Bezeichnung: PUF60

Hintergrund:

Background: This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: poly(U) binding splicing factor 60

Gen-ID: 22827

UniProt: Q9UHX1