PARP9 Antikörper (AA 117-824) (Cy3)

Produktnummer ABIN8023877

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PARP9 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PARP9 Antikörper (AA 117-824) (Cy3) (ABIN8023877)

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP9 Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PARP9 Antikörper (Cy3)

Bindungsspezifität: AA 117-824

Verwendungszweck: Anti-PARP9 Antibody Cy3 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PARP9 recombinant protein (Position: R117-E824).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PARP9

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Andere Bezeichnung: PARP9

Hintergrund:

Background: Poly (ADP-ribosyl)ation is a post-translational modification of proteins mediated by one of the 17 members of the poly (ADP-ribose) polymerases (PARP). PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFNγ, inducing the transcription of IFNγ-controlled genes.

Gene Full Name: poly(ADP-ribose) polymerase family member 9

Gen-ID: 83666

UniProt: Q8IXQ6