PIF1 Antikörper (AA 31-618) (Fluoro488)

Produktnummer ABIN8022548

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIF1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PIF1 Antikörper (AA 31-618) (Fluoro488) (ABIN8022548)

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIF1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PIF1 Antikörper (Fluoro488)

Bindungsspezifität: AA 31-618

Verwendungszweck: Anti-PIF1 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PIF1 shares 87.6%,87.8% amino acid (aa) sequence identity with mouse,rat PIF1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PIF1 recombinant protein (Position: Q31-R618). Human PIF1 shares 87.6% and 87.8% amino acid (aa) sequence identity with mouse and rat PIF1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PIF1

Target: PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))

Andere Bezeichnung: PIF1

Hintergrund:

Background: This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.

Gene Full Name: PIF1 5'-to-3' DNA helicase

Gen-ID: 80119

UniProt: Q9H611