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IRGM Antikörper (AA 51-150) (Cy3)

This anti-IRGM antibody (ABIN752566) is a Rabbit Polyclonal antibody detecting IRGM in WB, IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN752566

Kurzübersicht für IRGM Antikörper (AA 51-150) (Cy3) (ABIN752566)

Target

Alle IRGM Antikörper anzeigen
IRGM (Immunity-Related GTPase Family, M (IRGM))

Reaktivität

  • 35
  • 6
  • 2
Human

Wirt

  • 33
  • 4
Kaninchen

Klonalität

  • 33
  • 4
Polyklonal

Konjugat

  • 13
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IRGM Antikörper ist konjugiert mit Cy3

Applikation

  • 30
  • 15
  • 12
  • 12
  • 7
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    Homologie

    Human,Mouse,Rat,Dog

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human IRGM

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    IRGM (Immunity-Related GTPase Family, M (IRGM))

    Andere Bezeichnung

    IRGM

    Hintergrund

    Synonyms: Irgm, I1, Iigp3, Immunity related GTPase family M protein 1, Immunity related GTPase family, M, Interferon inducible protein 1, IRGM1, LRG 47, LRG47, IRGM_HUMAN.

    Background: IRGM belongs to a family of interferon-gamma inducible GTPases, belonging to the GTPase superfamily, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation. IRGM is primarily expressed in all cells derived from B-cell lineages, and is highly expressed in macrophages following IFN-gamma stimulation. IRGM has been shown to be required for host defences against a broad range of intracellular pathogens. Specifically, IRGM deficient mice show defects with intracellular microbial killing, phagosome maturation and autophagy. More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli.

    Gen-ID

    345611
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