PLD1 Antikörper (AA 1-330) (HRP)

Produktnummer ABIN8022219

Der Kaninchen Polyklonal anti-PLD1 Antikörper wird verwendet zum Nachweis von PLD1 in Proben von Human und Maus. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für PLD1 Antikörper (AA 1-330) (HRP) (ABIN8022219)

Target: PLD1 (Phospholipase D1 (PLD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLD1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PLD1 Antikörper (HRP)

Bindungsspezifität: AA 1-330

Verwendungszweck: Anti-Phospholipase D1/PLD1 Antibody HRP Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human PLD1 shares 91.8%,90.9% amino acid (aa) sequence identity with mouse,rat PLD1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PLD1

Target: PLD1 (Phospholipase D1 (PLD1))

Andere Bezeichnung: PLD1

Hintergrund:

Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

Gene Full Name: phospholipase D1

Sequence Similarities: Belongs to the phospholipase D family.

Gen-ID: 5337

UniProt: Q13393