PDE8A Antikörper (AA 32-495) (HRP)

Produktnummer ABIN8021552

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDE8A in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PDE8A Antikörper (AA 32-495) (HRP) (ABIN8021552)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8A Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PDE8A Antikörper (HRP)

Bindungsspezifität: AA 32-495

Verwendungszweck: Anti-PDE8A Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PDE8A recombinant protein (Position: R32-E495). Human PDE8A shares 80.5% amino acid (aa) sequence identity with mouse PDE8A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Andere Bezeichnung: PDE8A

Hintergrund:

Background: High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A is an enzyme that in humans is encoded by the PDE8A gene. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phosphodiesterase 8A

Gen-ID: 5151

UniProt: O60658

Pathways: cAMP Metabolic Process