PHF8 Antikörper (AA 108-946) (PE)

Produktnummer ABIN8021051

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHF8 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PHF8 Antikörper (AA 108-946) (PE) (ABIN8021051)

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF8 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-PHF8 Antikörper (PE)

Bindungsspezifität: AA 108-946

Verwendungszweck: Anti-PHF8 Antibody PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Andere Bezeichnung: PHF8

Hintergrund:

Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PHD finger protein 8

Gen-ID: 23133

UniProt: Q9UPP1