PHF8 Antikörper (AA 108-946) (HRP)

Produktnummer ABIN8021049

Der Kaninchen Polyklonal anti-PHF8 Antikörper wird verwendet zum Nachweis von PHF8 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für PHF8 Antikörper (AA 108-946) (HRP) (ABIN8021049)

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF8 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PHF8 Antikörper (HRP)

Bindungsspezifität: AA 108-946

Verwendungszweck: Anti-PHF8 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Andere Bezeichnung: PHF8

Hintergrund:

Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PHD finger protein 8

Gen-ID: 23133

UniProt: Q9UPP1