Peroxiredoxin 2 Antikörper (AA 5-127)

Produktnummer ABIN8020604

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Peroxiredoxin 2 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Peroxiredoxin 2 Antikörper (AA 5-127) (ABIN8020604)

Target: Peroxiredoxin 2 (PRDX2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Güteklasse: Carrier-free

Produktdetails anti-Peroxiredoxin 2 Antikörper

Bindungsspezifität: AA 5-127

Verwendungszweck: Anti-peroxiredoxin 2/PRDX2 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-peroxiredoxin 2/PRDX2 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human peroxiredoxin 2/PRDX2 recombinant protein (Position: N5-R127).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Andere Bezeichnung: PRDX2

Hintergrund:

Background: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a?protein?that in humans is encoded by the?PRDX2?gene. This gene encodes a member of the peroxiredoxin family of antioxidant?enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.?The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The?Prdx2?-/- mice were healthy in appearance and fertile. Choi et al.(2005)?demonstrated that?PRDX2?is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

Gene Full Name: peroxiredoxin 2

Molekulargewicht: 22 kDa

Gen-ID: 7001

UniProt: P32119