Peroxiredoxin 2 Antikörper (AA 5-127) (PE)

Produktnummer ABIN8020602

Der Kaninchen Polyklonal anti-Peroxiredoxin 2 Antikörper wird verwendet zum Nachweis von Peroxiredoxin 2 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für Peroxiredoxin 2 Antikörper (AA 5-127) (PE) (ABIN8020602)

Target: Peroxiredoxin 2 (PRDX2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Peroxiredoxin 2 Antikörper (PE)

Bindungsspezifität: AA 5-127

Verwendungszweck: Anti-peroxiredoxin 2/PRDX2 Antibody PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human peroxiredoxin 2/PRDX2 recombinant protein (Position: N5-R127).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Andere Bezeichnung: PRDX2

Hintergrund:

Background: PRDX2(peroxiredoxin 2) also known as NKEFB, PRP, PRX2, PRXII or TPX1, is a?protein?that in humans is encoded by the?PRDX2?gene. This gene encodes a member of the peroxiredoxin family of antioxidant?enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.?The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The?Prdx2?-/- mice were healthy in appearance and fertile. Choi et al.(2005)?demonstrated that?PRDX2?is a negative regulator of PDGF signaling. Prx II deficiency results in increased production of peroxide, enhanced activation of PDGF receptor and phospholipase C-gamma-1, and subsequently increased cell proliferation and migration in response to PDGF. PRX2 accounted for about half of the thioredoxin activity in parasite extracts, and PRX2 expression was increased in the presence of chloroquine, regardless of P. falciparum strain susceptibility to the drug.

Gene Full Name: peroxiredoxin 2

Gen-ID: 7001

UniProt: P32119