PEG3 Antikörper (AA 1-1548) (Biotin)

Produktnummer ABIN8019780

Der Kaninchen Polyklonal anti-PEG3 Antikörper wird verwendet zum Nachweis von PEG3 in Proben von Human. Er wurde validiert für WB, ELISA und IHC.

Kurzübersicht für PEG3 Antikörper (AA 1-1548) (Biotin) (ABIN8019780)

Target: PEG3 (Paternally Expressed 3 (PEG3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEG3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PEG3 Antikörper (Biotin)

Bindungsspezifität: AA 1-1548

Verwendungszweck: Anti-PEG3 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PEG3 recombinant protein (Position: M1-R1548). Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Andere Bezeichnung: PEG3

Hintergrund:

Background: Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene. In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: paternally expressed 3

Gen-ID: 5178

UniProt: Q9GZU2