Paired Box 3 Antikörper (AA 306-420)
Kurzübersicht für Paired Box 3 Antikörper (AA 306-420) (ABIN8019095)
Target
Alle Paired Box 3 (PAX3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- AA 306-420
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Verwendungszweck
- Anti-PAX3 Antibody
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Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
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Homologie
- Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.
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Produktmerkmale
- Anti-PAX3 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human PAX3 recombinant protein (Position: Q306-E420). Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.
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Isotyp
- IgG
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Applikationshinweise
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Haltbarkeit
- 12 months
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- Paired Box 3 (PAX3)
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Andere Bezeichnung
- PAX3
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Hintergrund
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Background: The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors. This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Gene Full Name: paired box 3
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Molekulargewicht
- 69 kDa
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Gen-ID
- 5077
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UniProt
- P23760
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Pathways
- Sensory Perception of Sound, Tube Formation
Target
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