POR Antikörper (C-Term)

Produktnummer ABIN8019040

Der Maus Monoklonal anti-POR Antikörper (Klon 7F5) (ABIN8019040) detektiert spezifisch POR in WB, IHC und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für POR Antikörper (C-Term) (ABIN8019040)

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser POR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: 7F5

Produktdetails anti-POR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-POR Antibody (monoclonal, 7F5)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: different from the related mouse,rat sequences by five amino acids.

Produktmerkmale: Anti-POR Antibody.(monoclonal, 7F5)-2. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human POR, different from the related mouse and rat sequences by five amino acids.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu POR

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Andere Bezeichnung: POR

Hintergrund:

Background: POR is a membrane-boundenzyme required for electron transfer from NADPH to cytochrome P450 in the endoplasmic reticulum of theeukaryotic cell. The gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons ly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Gene Full Name: cytochrome p450 oxidoreductase

Molekulargewicht: 77 kDa

Gen-ID: 5447

UniProt: P16435

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interaktom