P-Cadherin Antikörper (Middle Region) (Cy3)

Produktnummer ABIN8018932

Der Cy3-konjugierte Kaninchen Polyklonal anti-P-Cadherin Antikörper (ABIN8018932) detektiert spezifisch P-Cadherin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für P-Cadherin Antikörper (Middle Region) (Cy3) (ABIN8018932)

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P-Cadherin Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-P-Cadherin Antikörper (Cy3)

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-P-Cadherin-3 CDH3-Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the mouse,rat sequences by one amino acid.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human P cadherin, different from the mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3

Hintergrund:

Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Gene Full Name: cadherin 3

Sequence Similarities: Contains 5 cadherin domains.

Gen-ID: 1001

UniProt: P22223