Osteocalcin Antikörper (AA 52-100)

Produktnummer ABIN8018501

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Osteocalcin in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Osteocalcin Antikörper (AA 52-100) (ABIN8018501)

Target: Osteocalcin (BGLAP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Osteocalcin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-Osteocalcin Antikörper

Bindungsspezifität: AA 52-100

Verwendungszweck: Anti-Osteocalcin/BGLAP Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69%,80.9% amino acid (aa) sequence identity with mouse,rat Osteocalcin,respectively.

Produktmerkmale: Anti-Osteocalcin/BGLAP Antibody. Tested in IHC applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69% and 80.9% amino acid (aa) sequence identity with mouse and rat Osteocalcin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Osteocalcin

Target: Osteocalcin (BGLAP)

Andere Bezeichnung: BGLAP

Hintergrund:

Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

Gene Full Name: bone gamma-carboxyglutamate protein

Molekulargewicht: 29 kDa, 60 kDa

Gen-ID: 632

UniProt: P02818