Occludin Antikörper (AA 54-270) (Cy3)
Kurzübersicht für Occludin Antikörper (AA 54-270) (Cy3) (ABIN8017873)
Target
Alle Occludin (OCLN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 54-270
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Verwendungszweck
- Anti-Occludin/OCLN Antibody Cy3 Conjugated
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Occludin/OCLN recombinant protein (Position: H54-K270).
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Isotyp
- IgG
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Applikationshinweise
- Flow Cytometry, 1-3 μg/1x106 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- Occludin (OCLN)
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Andere Bezeichnung
- OCLN
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Hintergrund
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Background: Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.
Gene Full Name: occludin
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Gen-ID
- 100506658
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UniProt
- Q16625
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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