NSMCE4A Antikörper (AA 69-380) (Fluoro594)

Produktnummer ABIN8016070

Der Fluoro594-konjugierte Kaninchen Polyklonal anti-NSMCE4A Antikörper (ABIN8016070) detektiert spezifisch NSMCE4A in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NSMCE4A Antikörper (AA 69-380) (Fluoro594) (ABIN8016070)

Target: NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSMCE4A Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NSMCE4A Antikörper (Fluoro594)

Bindungsspezifität: AA 69-380

Verwendungszweck: Anti-NSMCE4A Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NSMCE4A recombinant protein (Position: D69-Q380).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NSMCE4A

Target: NSMCE4A (Non-SMC Element 4 Homolog A (NSMCE4A))

Andere Bezeichnung: NSMCE4A

Hintergrund:

Background: Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene. NSMCE4A is a component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). It is involved in positive regulation of response to DNA damage stimulus.

Gene Full Name: NSE4A component of SMC5/6 complex

Gen-ID: 54780

UniProt: Q9NXX6

Pathways: Positive Regulation of Response to DNA Damage Stimulus