NMNAT1 Antikörper (AA 56-279) (Fluoro488)

Produktnummer ABIN8015474

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NMNAT1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NMNAT1 Antikörper (AA 56-279) (Fluoro488) (ABIN8015474)

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMNAT1 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NMNAT1 Antikörper (Fluoro488)

Bindungsspezifität: AA 56-279

Verwendungszweck: Anti-NMNAT1 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NMNAT1 recombinant protein (Position: K56-T279). Human NMNAT1 shares 81.2% amino acid (aa) sequence identity with mouse NMNAT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Andere Bezeichnung: NMNAT1

Hintergrund:

Background: This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear deacetylase that functions in the protection of damaged neurons. Mutations in this gene have been associated with Leber congenital amaurosis 9. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14, and 15.

Gene Full Name: nicotinamide nucleotide adenylyltransferase 1

Gen-ID: 64802

UniProt: Q9HAN9