Neuropilin 1 Antikörper (AA 504-827) (APC)

Produktnummer ABIN8015072

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Neuropilin 1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Neuropilin 1 Antikörper (AA 504-827) (APC) (ABIN8015072)

Target: Neuropilin 1 (NRP1)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuropilin 1 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Neuropilin 1 Antikörper (APC)

Bindungsspezifität: AA 504-827

Verwendungszweck: Anti-Neuropilin 1/NRP1 Antibody APC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human Neuropilin 1 shares 95%,94% amino acid (aa) sequences identity with mouse,rat Neuropilin 1,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Neuropilin 1

Target: Neuropilin 1 (NRP1)

Andere Bezeichnung: NRP1

Hintergrund:

Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Full Name: neuropilin 1

Sequence Similarities: Belongs to the neuropilin family.

Gen-ID: 8829

UniProt: O14786

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals