NPS Antikörper (C-Term)

Produktnummer ABIN8014998

Der Kaninchen Polyklonal anti-NPS Antikörper wird verwendet zum Nachweis von NPS in Proben von Maus und Ratte. Er wurde validiert für IHC.

Kurzübersicht für NPS Antikörper (C-Term) (ABIN8014998)

Target: NPS (Neuropeptide S (NPS))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPS Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Güteklasse: Carrier-free

Produktdetails anti-NPS Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-Neuropeptide S/NPS Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Neuropeptide S/NPS Antibody. Tested in IHC applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Neuropeptide S, which shares 80% amino acid (aa) sequence identity with both mouse and rat Neuropeptide S.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NPS

Target: NPS (Neuropeptide S (NPS))

Andere Bezeichnung: NPS

Hintergrund:

Background: Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas. NPS binds specifically to a G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and appetite, induces wakefulness and hyperactivity, including hyper-sexuality, and plays a significant role in the extinction of conditioned fear.It has also been shown to significantly enhance dopamine activity in the mesolimbic pathway, and inhibits motility and increases permeability in neurocrine fashion acting through NO in the myenteric plexus in rats and humans.

Gene Full Name: neuropeptide S

Gen-ID: 594857

UniProt: P0C0P6