Neurogranin Antikörper (AA 11-54) (HRP)

Produktnummer ABIN8014796

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Neurogranin in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Neurogranin Antikörper (AA 11-54) (HRP) (ABIN8014796)

Target: Neurogranin (NRGN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurogranin Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Neurogranin Antikörper (HRP)

Bindungsspezifität: AA 11-54

Verwendungszweck: Anti-Neurogranin/NRGN Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NRGN recombinant protein (Position: K11-K54).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Neurogranin

Target: Neurogranin (NRGN)

Andere Bezeichnung: NRGN

Hintergrund:

Background: Neurogranin is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

Gene Full Name: neurogranin

Gen-ID: 4900

UniProt: Q92686