Neurexin 2 (NRXN2) (N-Term) Antikörper (HRP)

Produktnummer ABIN8014576

Der HRP-konjugierte Kaninchen Polyklonal anti-Neurexin 2 Antikörper (ABIN8014576) detektiert spezifisch Neurexin 2 in ELISA, WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte und Maus.

Kurzübersicht für Neurexin 2 (NRXN2) (N-Term) Antikörper (HRP) (ABIN8014576)

Target: Neurexin 2 (NRXN2)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: N-Term

Verwendungszweck: Anti-NRXN2 Antibody HRP Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse,rat NRXN2.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NRXN2. Human NRXN2 shares 100% amino acid (aa) sequence identity with both mouse and rat NRXN2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Neurexin 2 (NRXN2)

Andere Bezeichnung: NRXN2

Hintergrund:

Background: This gene encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).

Gene Full Name: neurexin 2

Gen-ID: 9379

UniProt: P58401

Pathways: Synaptic Membrane