NAE1 Antikörper (AA 181-534) (FITC)

Produktnummer ABIN8014168

Der FITC-konjugierte Kaninchen Polyklonal anti-NAE1 Antikörper (ABIN8014168) detektiert spezifisch NAE1 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NAE1 Antikörper (AA 181-534) (FITC) (ABIN8014168)

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAE1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NAE1 Antikörper (FITC)

Bindungsspezifität: AA 181-534

Verwendungszweck: Anti-APPBP1/NAE1 Antibody FITC Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human APPBP1 recombinant protein (Position: E181-L534). Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NAE1

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Andere Bezeichnung: NAE1

Hintergrund:

Background: NAE1 is also known as APPBP1. The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: NEDD8 activating enzyme E1 subunit 1

Gen-ID: 8883

UniProt: Q13564