NAD-ME Antikörper (AA 26-584) (Cy3)

Produktnummer ABIN8013339

Der Kaninchen Polyklonal anti-NAD-ME Antikörper wird verwendet zum Nachweis von NAD-ME in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für FACS.

Kurzübersicht für NAD-ME Antikörper (AA 26-584) (Cy3) (ABIN8013339)

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAD-ME Antikörper ist konjugiert mit Cy3

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NAD-ME Antikörper (Cy3)

Bindungsspezifität: AA 26-584

Verwendungszweck: Anti-ME2 Antibody Cy3 Conjugated

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ME2 recombinant protein (Position: K26-E584).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, 1-3 μg/1x10⁶ cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NAD-ME

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Andere Bezeichnung: ME2

Hintergrund:

Background: NAD-dependent malic enzyme, mitochondrial is a protein that in humans is encoded by the ME2 gene. It is mapped to 18q21.2. This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Gene Full Name: malic enzyme 2

Gen-ID: 4200

UniProt: P23368

Pathways: Production of Molecular Mediator of Immune Response