NANS Antikörper (AA 1-341) (PE)

Produktnummer ABIN8013015

Der Kaninchen Polyklonal anti-NANS Antikörper wird verwendet zum Nachweis von NANS in Proben von Human und Ratte. Er wurde validiert für FACS.

Kurzübersicht für NANS Antikörper (AA 1-341) (PE) (ABIN8013015)

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NANS Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-NANS Antikörper (PE)

Bindungsspezifität: AA 1-341

Verwendungszweck: Anti-NANS Antibody PE Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu NANS

Target: NANS (N-Acetylneuraminic Acid Synthase (NANS))

Andere Bezeichnung: NANS

Hintergrund:

Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Gene Full Name: N-acetylneuraminate synthase

Gen-ID: 54187

UniProt: Q9NR45