MYO1E Antikörper (AA 221-1065) (Fluoro647)

Produktnummer ABIN8012719

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-MYO1E Antikörper (ABIN8012719) detektiert spezifisch MYO1E in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MYO1E Antikörper (AA 221-1065) (Fluoro647) (ABIN8012719)

Target: MYO1E (Myosin IE (MYO1E))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYO1E Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MYO1E Antikörper (Fluoro647)

Bindungsspezifität: AA 221-1065

Verwendungszweck: Anti-MYO1E Antibody Fluoro647 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: Human MYO1E shares 95.9%,95.3% amino acid (aa) sequence identity with mouse,rat MYO1E,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MYO1E recombinant protein (Position: A221-Q1065). Human MYO1E shares 95.9% and 95.3% amino acid (aa) sequence identity with mouse and rat MYO1E, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MYO1E

Target: MYO1E (Myosin IE (MYO1E))

Andere Bezeichnung: MYO1E

Hintergrund:

Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Gene Full Name: myosin IE

Gen-ID: 4643

UniProt: Q12965

Pathways: Platelet-derived growth Factor Receptor Signaling