MIOX Antikörper (AA 1-266) (APC)

Produktnummer ABIN8012529

Der Kaninchen Polyklonal anti-MIOX Antikörper wird verwendet zum Nachweis von MIOX in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für MIOX Antikörper (AA 1-266) (APC) (ABIN8012529)

Target: MIOX (Myo-Inositol Oxygenase (MIOX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MIOX Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MIOX Antikörper (APC)

Bindungsspezifität: AA 1-266

Verwendungszweck: Anti-MIOX Antibody APC Conjugated

Homologie: Human MIOX shares 89.8%,90.5% amino acid (aa) sequence identity with mouse,rat MIOX,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MIOX

Target: MIOX (Myo-Inositol Oxygenase (MIOX))

Andere Bezeichnung: MIOX

Hintergrund:

Background: Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.

Gene Full Name: myo-inositol oxygenase

Gen-ID: 55586

UniProt: Q9UGB7

Pathways: Inositol Metabolic Process