Menin Antikörper (AA 301-615) (Fluoro488)
Kurzübersicht für Menin Antikörper (AA 301-615) (Fluoro488) (ABIN8012040)
Target
Alle Menin (MEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-615
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Verwendungszweck
- Anti-Menin/MEN1 Antibody Fluoro488 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Menin shares 93%,94% amino acid (aa) sequence identity with mouse,rat Menin,respectively.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Menin recombinant protein (Position: P301-L615). Human Menin shares 93% and 94% amino acid (aa) sequence identity with mouse and rat Menin, respectively.
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Isotyp
- IgG
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anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 392-554) antibody
MEN1 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 7D3E10 unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 219-395) antibodyMEN1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 501-615) antibodyMEN1 Reaktivität: Human, Maus, Ratte ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 1-575) antibodyMEN1 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (Internal Region) antibodyMEN1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (AA 584-615) antibodyMEN1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB0543 unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) (C-Term) antibodyMEN1 Reaktivität: Human, Maus WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
anti-Multiple Endocrine Neoplasia 1 (MEN1) antibodyKD Validated MEN1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB2590 unconjugated Recombinant Antibody
anti-Multiple Endocrine Neoplasia 1 (MEN1) (C-Term) antibodyMEN1 Reaktivität: Human, Maus WB, ChIP, ChIP-seq Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Flow Cytometry, Optimal dilutions should be determined by end users.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
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Andere Bezeichnung
- MEN1
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Hintergrund
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Background: The MEN1 gene encodes menin, a nuclear scaffold protein that regulates gene transcription by coordinating chromatin remodeling. It is mapped to 11q13.1. MEN1 is considered to act as a tumor suppressor gene. It has been found that that MEN1 inactivation by antisense RNA antagonizes transforming growth factor-beta-mediated cell growth inhibition. Overexpression of MEN1 in an inducible cell culture system downregulated the proximal promoter. In vitro studies have shown that MEN1 is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD. What's more, MEN1 was essential to maintain MLL-associated myeloid transformation.
Gene Full Name: menin 1
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Gen-ID
- 4221
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UniProt
- O00255
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Pathways
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
Target
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