MFAP3 Antikörper (AA 19-349) (Biotin)

Produktnummer ABIN8009958

Der Kaninchen Polyklonal anti-MFAP3 Antikörper wird verwendet zum Nachweis von MFAP3 in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, WB und IHC.

Kurzübersicht für MFAP3 Antikörper (AA 19-349) (Biotin) (ABIN8009958)

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MFAP3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MFAP3 Antikörper (Biotin)

Bindungsspezifität: AA 19-349

Verwendungszweck: Anti-MFAP3 Antibody Biotin Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MFAP3 recombinant protein (Position: A19-N349).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MFAP3

Target: MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))

Andere Bezeichnung: MFAP3

Hintergrund:

Background: Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities. MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74 % amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils.

Gene Full Name: microfibril associated protein 3

Gen-ID: 4238

UniProt: P55082