MVK Antikörper (AA 13-394) (FITC)

Produktnummer ABIN8009875

Der FITC-konjugierte Kaninchen Polyklonal anti-MVK Antikörper (ABIN8009875) detektiert spezifisch MVK in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MVK Antikörper (AA 13-394) (FITC) (ABIN8009875)

Target: MVK (Mevalonate Kinase (MVK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MVK Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MVK Antikörper (FITC)

Bindungsspezifität: AA 13-394

Verwendungszweck: Anti-MVK Antibody FITC Conjugated

Homologie: Human MVK shares 80.8%,81.4% amino acid (aa) sequence identity with mouse,rat MVK,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MVK recombinant protein (Position: K13-D394). Human MVK shares 80.8% and 81.4% amino acid (aa) sequence identity with mouse and rat MVK, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MVK

Target: MVK (Mevalonate Kinase (MVK))

Andere Bezeichnung: MVK

Hintergrund:

Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.

Gene Full Name: mevalonate kinase

Gen-ID: 4598

UniProt: Q03426