Melanophilin Antikörper (AA 61-523) (Fluoro647)

Produktnummer ABIN8008966

Der Fluoro647-konjugierte Kaninchen Polyklonal anti-Melanophilin Antikörper (ABIN8008966) detektiert spezifisch Melanophilin in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Melanophilin Antikörper (AA 61-523) (Fluoro647) (ABIN8008966)

Target: Melanophilin (MLPH)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melanophilin Antikörper ist konjugiert mit Fluoro647

Applikation: Flow Cytometry (FACS)

Produktdetails anti-Melanophilin Antikörper (Fluoro647)

Bindungsspezifität: AA 61-523

Verwendungszweck: Anti-MLPH Antibody Fluoro647 Conjugated

Homologie: Human Melanophilin,MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin,MLPH.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Melanophilin/MLPH recombinant protein (Position: E61-L523). Human Melanophilin/MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin/MLPH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu Melanophilin

Target: Melanophilin (MLPH)

Andere Bezeichnung: MLPH

Hintergrund:

Background: Melanophilin is a carrier protein which in humans is encoded by the MLPH gene. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: melanophilin

Gen-ID: 79083

UniProt: Q9BV36