MC4R Antikörper (C-Term)

Produktnummer ABIN8008857

Der Kaninchen Polyklonal anti-MC4R Antikörper wird verwendet zum Nachweis von MC4R in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, FACS, IF und ICC.

Kurzübersicht für MC4R Antikörper (C-Term) (ABIN8008857)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MC4R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Güteklasse: Carrier-free

Produktdetails anti-MC4R Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-MC4-R/MC4R Antibody

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MC4-R/MC4R Antibody-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MC4-R/MC4R, which shares 88.5% and 80.8% amino acid (aa) sequence identity with mouse and rat MC4-R/MC4R, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Andere Bezeichnung: MC4R

Hintergrund:

Background: Melanocortin receptor 4 is a protein that in humans is encoded by the MC4R gene. This gene is mapped to 18q21.32. The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.

Gene Full Name: melanocortin 4 receptor

Molekulargewicht: 37 kDa

Gen-ID: 4160

UniProt: P32245

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour