MDC1 Antikörper (AA 534-626) (Cy3)
Kurzübersicht für MDC1 Antikörper (AA 534-626) (Cy3) (ABIN8008441)
Target
Alle MDC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 534-626
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Verwendungszweck
- Anti-MDC1 Antibody Cy3 Conjugated
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E. coli-derived human MDC1 recombinant protein (Position: A534-Q626).
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Isotyp
- IgG
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anti-Mdc1 (MDC1) antibody
MDC1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 390)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Atto 390
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 488)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Atto 488
anti-Mdc1 (MDC1) (N-Term) antibody (Atto 594)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Atto 594
anti-Mdc1 (MDC1) (N-Term) antibody (FITC)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 FITC
anti-Mdc1 (MDC1) (N-Term) antibody (HRP)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 HRP
anti-Mdc1 (MDC1) (N-Term) antibody (APC)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 APC
anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 Biotin
anti-Mdc1 (MDC1) (N-Term) antibody (PerCP)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 PerCP
anti-Mdc1 (MDC1) (N-Term) antibody (PE)MDC1 Reaktivität: Maus WB, IF, ICC Wirt: Maus Monoclonal P2B11 PE
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Applikationshinweise
- Flow Cytometry, 1-3 μg/1x106 cells
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Haltbarkeit
- 12 months
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- MDC1 (Mdc1 (MDC1))
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Andere Bezeichnung
- MDC1
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Hintergrund
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Background: Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene. The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Gene Full Name: mediator of DNA damage checkpoint 1
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Gen-ID
- 9656
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UniProt
- Q14676
Target
-
