MMP20 Antikörper (AA 124-405) (Fluoro488)

Produktnummer ABIN8008332

Der Kaninchen Polyklonal anti-MMP20 Antikörper wird verwendet zum Nachweis von MMP20 in Proben von Human. Er wurde validiert für FACS.

Kurzübersicht für MMP20 Antikörper (AA 124-405) (Fluoro488) (ABIN8008332)

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP20 Antikörper ist konjugiert mit Fluoro488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-MMP20 Antikörper (Fluoro488)

Bindungsspezifität: AA 124-405

Verwendungszweck: Anti-MMP20 Antibody Fluoro488 Conjugated

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human MMP20 shares 91.5% amino acid (aa) sequence identity with mouse MMP20.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MMP20 recombinant protein (Position: Y124-K405). Human MMP20 shares 91.5% amino acid (aa) sequence identity with mouse MMP20.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu MMP20

Target: MMP20 (Matrix Metalloproteinase 20 (MMP20))

Andere Bezeichnung: MMP20

Hintergrund:

Background: Matrix metalloproteinase-20 (MMP-20) also known as enamel metalloproteinase or enamelysin is an enzyme that in humans is encoded by the MMP20 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.

Gene Full Name: matrix metallopeptidase 20

Gen-ID: 9313

UniProt: O60882