Macro H2A.2 (AA 181-340) Antikörper

Produktnummer ABIN8007207

Der Kaninchen Polyklonal anti-Macro H2A.2 Antikörper wird verwendet zum Nachweis von Macro H2A.2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC, FACS, IF und ICC.

Kurzübersicht für Macro H2A.2 (AA 181-340) Antikörper (ABIN8007207)

Target: Macro H2A.2

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Güteklasse: Carrier-free

Produktdetails

Bindungsspezifität: AA 181-340

Verwendungszweck: Anti-H2AFY2/MACROH2A2 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human MACROH2A2 shares 99.4% amino acid (aa) sequence identity with mouse MACROH2A2.

Produktmerkmale: Anti-H2AFY2/MACROH2A2 Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human H2AFY2/MACROH2A2 recombinant protein (Position: D181-D340). Human MACROH2A2 shares 99.4% amino acid (aa) sequence identity with mouse MACROH2A2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Macro H2A.2

Andere Bezeichnung: MACROH2A2

Hintergrund:

Background: Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation.

Gene Full Name: macroH2A.2 histone

Molekulargewicht: 40 kDa

Gen-ID: 55506

UniProt: Q9P0M6