LYAR Antikörper (AA 1-379) (HRP)

Produktnummer ABIN8006740

Der HRP-konjugierte Kaninchen Polyklonal anti-LYAR Antikörper (ABIN8006740) detektiert spezifisch LYAR in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für LYAR Antikörper (AA 1-379) (HRP) (ABIN8006740)

Target: LYAR (Ly1 Antibody Reactive (LYAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LYAR Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-LYAR Antikörper (HRP)

Bindungsspezifität: AA 1-379

Verwendungszweck: Anti-LYAR Antibody HRP Conjugated

Homologie: Human LYAR shares 71.9%,73.7% amino acid (aa) sequence identity with mouse,rat LYAR,respectively.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LYAR recombinant protein (Position: M1-K379). Human LYAR shares 71.9% and 73.7% amino acid (aa) sequence identity with mouse and rat LYAR, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu LYAR

Target: LYAR (Ly1 Antibody Reactive (LYAR))

Andere Bezeichnung: LYAR

Substanzklasse: Antibody

Hintergrund:

Background: Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene (Ly-1 antibody reactive clone). LYAR (Ly-1/CD5 antibody reactive clone) is a 45-50 kDa nucleolar protein that was named for the ability of its antibody to cross-react with Ly-1. Its function is unclear, it is known to associate with MYCN and RRP1B, the latter association giving rise to the suggestion that LYAR is involved with RNA metabolism. Human LYAR is 379 amino acids (aa) in length. It contains two C2H2-type Zn finger regions (aa 6-25 and 33-51) followed by one coiled-coil region (aa 175-219) and an NLS (aa 217-222). There are multiple Zn-binding sites and three utilized phosphorylation sites at Ser244, Ser258 and Ser276. Over aa 288-379, human LYAR shares 75 % aa identity with mouse LYAR.

Gene Full Name: Ly1 antibody reactive

Gen-ID: 55646

UniProt: Q9NX58