LNPEP Antikörper (AA 17-994) (Fluoro594)

Produktnummer ABIN8005836

Der Kaninchen Polyklonal anti-LNPEP Antikörper wird verwendet zum Nachweis von LNPEP in Proben von Human, Ratte und Maus. Er wurde validiert für FACS.

Kurzübersicht für LNPEP Antikörper (AA 17-994) (Fluoro594) (ABIN8005836)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNPEP Antikörper ist konjugiert mit Fluoro594

Applikation: Flow Cytometry (FACS)

Produktdetails anti-LNPEP Antikörper (Fluoro594)

Bindungsspezifität: AA 17-994

Verwendungszweck: Anti-LNPEP Antibody Fluoro594 Conjugated

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LNPEP recombinant protein (Position: E17-T994).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry, Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Haltbarkeit: 12 months

Details zu LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Andere Bezeichnung: LNPEP

Hintergrund:

Background: Leucyl/cystinyl aminopeptidase, also known as cystinyl aminopeptidase (CAP), insulin-regulated aminopeptidase (IRAP), human placental leucine aminopeptidase (PLAP), oxytocinase, and vasopressinase, is an enzyme of the aminopeptidase group that in humans is encoded by the LNPEP gene. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: leucyl and cystinyl aminopeptidase

Gen-ID: 4012

UniProt: Q9UIQ6

Pathways: Regulation of long-term Neuronal Synaptic Plasticity